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J Cell Biol. 2019 Feb 4;218(2):387-388. doi: 10.1083/jcb.201812051. Epub 2019 Jan 15.

Dendritic cells mature to resist lamin degradation and herpes virus release.

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1
Institut National de la Santé et de la Recherche Médicale, U1016, Institut Cochin, Paris, France Florence.niedergang@inserm.fr.

Abstract

Herpes simplex viruses bud into the nuclear membrane of infected cells. Turan et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201801151) demonstrate that mature dendritic cells control the peripheral location of lysosomes, reducing autophagic degradation of lamins and inhibiting viral release.

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