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J Cell Biol. 2019 Feb 4;218(2):387-388. doi: 10.1083/jcb.201812051. Epub 2019 Jan 15.

Dendritic cells mature to resist lamin degradation and herpes virus release.

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Institut National de la Santé et de la Recherche Médicale, U1016, Institut Cochin, Paris, France


Herpes simplex viruses bud into the nuclear membrane of infected cells. Turan et al. (2019. J. Cell Biol. demonstrate that mature dendritic cells control the peripheral location of lysosomes, reducing autophagic degradation of lamins and inhibiting viral release.

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