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Circ Genom Precis Med. 2019 Jan;12(1):e002335. doi: 10.1161/CIRCGEN.118.002335.

Variation in Serum PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9), Cardiovascular Disease Risk, and an Investigation of Potential Unanticipated Effects of PCSK9 Inhibition.

Author information

1
Department of Public Health and Nursing, K.G. Jebsen Center for Genetic Epidemiology (B.M.B., L.G.F., H.R., G.Å.V., M.E.G., K.H., B.O.Å.), NTNU, Norwegian University of Science and Technology, Trondheim.
2
MRC Integrative Epidemiology Unit, University of Bristol, United Kingdom (B.M.B., J.Z., H.R., G.D.S.).
3
Clinic of Thoracic and Occupational Medicine (B.M.B.), St. Olavs Hospital, Trondheim University Hospital, Norway.
4
Department of Biostatistics and Center for Statistical Genetics (L.G.F., C.W.), University of Michigan, Ann Arbor, MI.
5
Department of Internal Medicine (J.B.N., I.S., S.E.G., C.W.), University of Michigan, Ann Arbor, MI.
6
Cardiology Unit (M.M.), Karolinska Institutet, Stockholm, Sweden.
7
Cardiovascular Medicine Unit, Department of Medicine Solna, Center for Molecular Medicine (M.M., F.M.v.H.), Karolinska Institutet, Stockholm, Sweden.
8
Department of Public Health and Nursing (G.Å.V., L.E.L., L.J.V., I.J.), NTNU, Norwegian University of Science and Technology, Trondheim.
9
Department of Circulation and Medical Imaging (L.E.L.), NTNU, Norwegian University of Science and Technology, Trondheim.
10
Department of Cardiology (L.E.L.), St. Olavs Hospital, Trondheim University Hospital, Norway.
11
Research Institute of Internal Medicine (P.A., T.U.), Oslo University Hospital, Rikshospitalet.
12
Section of Clinical Immunology and Infectious Diseases (P.A.), Oslo University Hospital, Rikshospitalet.
13
Institute of Clinical Medicine (P.A.), University of Oslo, Norway.
14
Department of Clinical and Molecular Medicine, Centre of Molecular Inflammation Research (J.K.D.), NTNU, Norwegian University of Science and Technology, Trondheim.
15
Department of Infectious Diseases (J.K.D.), St. Olavs Hospital, Trondheim University Hospital, Norway.
16
University of Oslo, Norway (T.U.).
17
K.G. Jebsen TREC, University of Tromsø, Norway (T.U.).
18
Division of Clinical Neuroscience, Oslo University Hospital (J.-A.Z.), University of Oslo, Norway.
19
Laboratory of Biochemical Neuroendocrinology, IRCM, Montreal, Quebec, Canada (N.G.S.).
20
Department of Human Genetics (C.W.), University of Michigan, Ann Arbor, MI.
21
Department of Endocrinology (B.O.Å.), St. Olavs Hospital, Trondheim University Hospital, Norway.

KEYWORDS:

cardiovascular diseases; hospital records; lipids; lung; mental health; pain

PMID:
30645169
DOI:
10.1161/CIRCGEN.118.002335

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