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J Epidemiol. 2019 Jan 12. doi: 10.2188/jea.JE20180130. [Epub ahead of print]

Association of vegetable, fruit, and Okinawan vegetable consumption with incident stroke and coronary heart disease.

Author information

1
Department of Food and Life Sciences, Faculty of Food and Nutritional Sciences, Toyo University.
2
School of Life and Environmental Science, Department of Food and Life Science, Azabu University.
3
Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center.
4
Department of Preventive Cardiology, National Cerebral and Cardiovascular Center.
5
Department of Community Health Systems Nursing, Ehime Graduate School of Medicine.
6
Department of Public Health, School of Medicine, Fujita Health University.
7
Department of Public Health Medicine, Faculty of Medicine, University of Tsukuba.
8
Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine.

Abstract

BACKGROUND:

Few studies have investigated the effects of Okinawan vegetable consumption on the risk of incident stroke and coronary heart disease. This study aimed to examine associations of vegetable, fruit, and Okinawan vegetable consumption with risk of incident stroke and coronary heart disease in the Japanese population of Okinawa.

METHODS:

Study design was a prospective cohort study. During 1995-1998, a validated food frequency questionnaire was administered in two study areas to 16,498 participants aged 45-74 years. In 217,467 person-years of follow-up until the end of 2012, a total of 839 stroke cases and 197 coronary heart disease cases were identified.

RESULTS:

No statistically significant association between total Okinawan vegetable consumption and risk of stroke and coronary heart disease was obtained: the multivariable adjusted hazard ratios for the highest versus lowest tertile of consumption were 1.09 (95% confidence interval, 0.93-1.29; p for trend = 0.289) in model 2. Total vegetable and fruit and specific Okinawan vegetable consumption were also not statistically significantly associated with risk of cardiovascular outcomes.

CONCLUSIONS:

This study demonstrated that consumption of total vegetable and fruit, total Okinawan vegetables, and specific Okinawan vegetables in Japanese residents of Okinawa was not associated with risk of incident stroke and coronary heart disease.

KEYWORDS:

Cohort study; Okinawan vegetable; cardiovascular disease

PMID:
30643101
DOI:
10.2188/jea.JE20180130
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