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Mult Scler Relat Disord. 2019 Feb;28:273-275. doi: 10.1016/j.msard.2019.01.018. Epub 2019 Jan 6.

Pulmonary arterial hypertension associated with interferon-beta treatment for multiple sclerosis. Case report and literature review.

Author information

1
Onassis Cardiac Surgery Center, Noninvasive Department of Cardiology, Athens, Greece. Electronic address: efidemer@otenet.gr.
2
Onassis Cardiac Surgery Center, Interventional Department of Cardiology, Athens, Greece.
3
Onassis Cardiac Surgery Center, Noninvasive Department of Cardiology, Athens, Greece.
4
Mediterraneo Hospital, Interventional Cardiology and Cardiology Department, Athens, Greece.

Abstract

Drug-Induced Pulmonary Arterial Hypertension (PAH) represents a well-known entity, predominantly related to anorexigens. Interferon-β (IFN) is considered to be a drug with a possible risk of inducing PAH. We report a patient with Multiple Sclerosis treated with IFN-β who diagnosed with PAH and her course of disease under specific PAH drug therapy. A review of the literature in IFN-β-induced PAH is provided.

KEYWORDS:

Interferon-β; Multiple sclerosis; Pulmonary arterial hypertension

PMID:
30639829
DOI:
10.1016/j.msard.2019.01.018
[Indexed for MEDLINE]

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