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Clin J Am Soc Nephrol. 2019 Jan 9. pii: CJN.10330818. doi: 10.2215/CJN.10330818. [Epub ahead of print]

The Use of Selected Urine Chemistries in the Diagnosis of Kidney Disorders.

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Division of Nephrology, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas; and
Department of Internal Medicine, University of California, Los Angeles School of Medicine, Los Angeles, California.


Urinary chemistries vary widely in both health and disease and are affected by diet, volume status, medications, and disease states. When properly examined, these tests provide important insight into the mechanism and therapy of various clinical disorders that are first detected by abnormalities in plasma chemistries. These tests cannot be interpreted in isolation, but instead require knowledge of key clinical information, such as medications, physical examination, and plasma chemistries, to include kidney function. When used appropriately and with knowledge of limitations, urine chemistries can provide important insight into the pathophysiology and treatment of a wide variety of disorders.


Diagnostic Tests; Diet; Physical Examination; Routine; Urinary Tract Physiological Phenomena; Urologic Diseases


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