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PLoS One. 2019 Jan 7;14(1):e0207208. doi: 10.1371/journal.pone.0207208. eCollection 2019.

Voided volume < 150 mL on initial uroflowmetry in men with storage symptoms: Is it an unreliable test result or a sign of severe storage symptoms?

Author information

1
Department of Urology, Seoul National University Boramae Medical Center, Seoul, South Korea.
2
Department of Urology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.

Abstract

PURPOSE:

To assess the utility of voided volume on initial uroflowmetry in predicting symptom severity in men with storage symptoms. In addition, we assessed the probability that men would show a voided volume of ≥ 150 mL on uroflowmetry if the examination is repeated.

METHODS:

Between 2016 and 2017, 352 men with storage symptoms were enrolled in the study. The patients completed the frequency-volume chart and were divided into four groups based on the voided volume. A multivariate analysis was performed to determine the variables affecting voided volume.

RESULTS:

The VV was < 68.8 mL in 88 patients (25.0%), 68.9-150 in 89 (25.3%), 150-250 in 87 (24.7%), and ≥ 250 in 88 (25.0%) patients. Although the International Prostate Symptom Score did not differ among the groups, the storage subscore was significantly higher in patients with decreased voided volume (p = 0.010). The total number of voids was greater in patients with decreased voided volume (p < 0.001), as was the number of nocturnal voids (p = 0.007). The maximum voided volume (p < 0.001) and 24-h urine output (p = 0.003) decreased as voided volume decreased. The proportions of patients with a mean daytime urine output ≥ 150 mL were 30.1%, 43.0%, 64.7%, and 66.7% in each group, respectively (p < 0.001). Older age and decreased maximum voided volume significantly affected the voided volume on initial uroflowmetry.

CONCLUSIONS:

A decreased voided volume on initial uroflowmetry may be a sign of severe storage symptoms in men. This finding is related to older age and decreased functional capacity. In these patients, it is better to perform a careful clinical assessment to diagnose and treat overactive bladder.

Conflict of interest statement

The authors have declared that no competing interests exist.

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