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J Vasc Surg Venous Lymphat Disord. 2019 May;7(3):375-381. doi: 10.1016/j.jvsv.2018.10.016. Epub 2019 Jan 3.

Regression of varicose veins after cyanoacrylate closure of incompetent great saphenous veins without a localized concomitant procedure.

Author information

1
Department of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea.
2
Department of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea. Electronic address: psw0224@kuh.ac.kr.
3
Department of Thoracic and Cardiovascular Surgery, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea.
4
Department of Surgery, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea.

Abstract

OBJECTIVE:

The objective of this study was to evaluate the effectiveness and safety of endovenous cyanoacrylate closure (CAC) of incompetent great saphenous vein (GSV) and to assess the regression of varicose vein following CAC without a concomitant procedure.

METHODS:

A total of 63 limbs in 48 patients treated with CAC because of an incompetent GSV between December 2016 and November 2017 were retrospectively evaluated. In five limbs, incompetent GSV and small saphenous vein were treated simultaneously in the same session. Duplex ultrasound, Venous Clinical Severity Score, degree of regression of varicose veins, and adverse events were examined at intervals of 1 week, 1 month, 3 months, 6 months, and 12 months.

RESULTS:

In 63 limbs, of which 60 were available for follow-up, all treated GSVs showed complete closure during the follow-up period (8.4 ± 3.0 months). Venous Clinical Severity Scores at the time of all follow-up visits were significantly lower (P < .001) than those before CAC. Complete resolution of varicose veins was noted in 38 limbs (71.7%) after 3-month follow-up. The proportion of limbs showing >50% varicose vein regression reached 90.6%. The more that varicosity entry was covered (P = .002) and the farther down the leg the access site was located (P = .024), the more complete resolution of varicose veins was observed. Phlebitis occurred in 10 limbs (16.7%), and hyperpigmentation occurred in 8 limbs (13.3%).

CONCLUSIONS:

CAC is safe and effective for the treatment of an incompetent GSV. It also shows a satisfactory result with the regression of varicose veins. Covering the entry of varicosities and accessing lower down the leg are associated with more complete resolution of varicose veins.

KEYWORDS:

Cyanoacrylate; Great saphenous vein; Regression; Varicose vein

PMID:
30612973
DOI:
10.1016/j.jvsv.2018.10.016

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