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Molecules. 2019 Jan 2;24(1). pii: E155. doi: 10.3390/molecules24010155.

Biosynthesis, Chemistry, and Pharmacology of Polyphenols from Chinese Salvia Species: A Review.

Author information

1
Inner Mongolia Research Center of Characteristic Medicinal Plants Cultivation and Protection Engineering Technology, Baotou Medical College, Baotou 014060, Inner Mongolia, China. yiuje_sgnaw@outlook.com.
2
Inner Mongolia Research Center of Characteristic Medicinal Plants Cultivation and Protection Engineering Technology, Baotou Medical College, Baotou 014060, Inner Mongolia, China. xu_jianping1992@163.com.
3
Inner Mongolia Research Center of Characteristic Medicinal Plants Cultivation and Protection Engineering Technology, Baotou Medical College, Baotou 014060, Inner Mongolia, China. gongxue_2017@yeah.net.
4
Inner Mongolia Research Center of Characteristic Medicinal Plants Cultivation and Protection Engineering Technology, Baotou Medical College, Baotou 014060, Inner Mongolia, China. yangmin_0406@aliyun.com.
5
Inner Mongolia Research Center of Characteristic Medicinal Plants Cultivation and Protection Engineering Technology, Baotou Medical College, Baotou 014060, Inner Mongolia, China. zchlhh@126.com.
6
Inner Mongolia Research Center of Characteristic Medicinal Plants Cultivation and Protection Engineering Technology, Baotou Medical College, Baotou 014060, Inner Mongolia, China. prof_liminhui@yeah.net.
7
Inner Mongolia Institute of Traditional Chinese Medicine, Hohhot 010020, Inner Mongolia, China. prof_liminhui@yeah.net.

Abstract

Salvia species find widespread application in food and pharmaceutical products owing to their large polyphenol content. The main polyphenols in Chinese Salvia species are phenolic acids and flavonoids, which exhibit anti-oxygenation, anti-ischemia-reperfusion injury, anti-thrombosis, anti-tumour, and other therapeutic effects. However, there are few peer-reviewed studies on polyphenols in Chinese Salvia species, especially flavonoids. This review is a systematic, comprehensive collation of available information on the biosynthesis, chemistry, and pharmacology of Chinese Salvia species. We believe that our study makes a significant contribution to the literature because this review provides a detailed literary resource on the currently available information on various polyphenolic components of Chinese Salvia species, including their bioactivities and structures. In addition, the study provides information that would encourage further investigation of this plant material as a natural resource with potential for a broad range of applications in various industries, such as the food and pharmaceutical industries.

KEYWORDS:

Salvia; biosynthesis; chemistry; pharmacology; phenolic acids; polyphenols

PMID:
30609767
PMCID:
PMC6337547
DOI:
10.3390/molecules24010155
[Indexed for MEDLINE]
Free PMC Article

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