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Neuron. 2019 Jan 2;101(1):15-19. doi: 10.1016/j.neuron.2018.12.016.

The NeuroDev Study: Phenotypic and Genetic Characterization of Neurodevelopmental Disorders in Kenya and South Africa.

Author information

1
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, UK; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02142, USA.
2
Department of Paediatrics & Child Health, 4(th) Floor ICH Building, Red Cross War Memorial Children's Hospital and University of Cape Town, Rondebosch, South Africa.
3
Neurosciences Unit, Clinical Department, KEMRI-Wellcome Trust Collaborative Research Programme, PO Box 230-80108, Kilifi, Kenya.
4
Department of Health Systems and Research Ethics, KEMRI-Wellcome Trust Collaborative Research Programme, Kilifi, Kenya.
5
Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02142, USA; Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA.
6
Department of Medicine, University of Cape Town, Observatory, Cape Town 7925, South Africa.
7
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, UK; Neurosciences Unit, Clinical Department, KEMRI-Wellcome Trust Collaborative Research Programme, PO Box 230-80108, Kilifi, Kenya.
8
Department of Psychiatry and Wellcome Centre for Ethics and Humanities, University of Oxford, Oxford, UK.
9
Department of Psychiatry & Mental Health, and MRC Unit on Risk and Resilience in Mental Disorders, University of Cape Town, J-Block, Groote Schuur Hospital, Observatory, Cape Town, South Africa.
10
Neurosciences Unit, Clinical Department, KEMRI-Wellcome Trust Collaborative Research Programme, PO Box 230-80108, Kilifi, Kenya. Electronic address: aabubakar@kemri-wellcome.org.
11
Department of Paediatrics & Child Health, 4(th) Floor ICH Building, Red Cross War Memorial Children's Hospital and University of Cape Town, Rondebosch, South Africa. Electronic address: kirsty.donald@uct.ac.za.
12
Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02142, USA; Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Richard B. Simches Building, 6(th) Floor, 185 Cambridge Street, Boston, MA 02114, USA. Electronic address: erob@broadinstitute.org.

Abstract

The NeuroDev study will deeply phenotype cognition, behavior, dysmorphias, and neuromedical traits on an expected cohort of 5,600 Africans (1,800 child cases, 1,800 child controls, and 1,900 parents) and will collect whole blood for exome sequencing and biobanking.

PMID:
30605655
DOI:
10.1016/j.neuron.2018.12.016
[Indexed for MEDLINE]
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