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Rev Alerg Mex. 2018 Oct-Dec;65(4):379-388. doi: 10.29262/ram.v65i4.513.

[Perioperative allergy. A 3-year experience].

[Article in Spanish; Abstract available in Spanish from the publisher]

Author information

1
Secretaría de Salud, Hospital General de México, Servicio Alergia e Inmunología Clínica, Ciudad de México, México. rodnova87@hotmail.com.

Abstract

in English, Spanish

BACKGROUND:

Perioperative hypersensitivity reactions constitute a global health problem, with an estimated incidence of 1 per 100,000 procedures and a mortality rate of 0.1 to 9 %. Main risk factors are a history of allergy to other drugs, atopy, associated psychiatric disorders and previous surgeries.

OBJECTIVES:

To determine the frequency of sensitization and the type of drugs involved in perioperative allergy in a tertiary care hospital, over a 3-year period.

METHODS:

Retrospective, cross-sectional, descriptive study of perioperative allergy, corroborated by skin tests for each drug and latex, of patients treated at the Allergy and Clinical Immunology Department of Hospital General de Mexico.

RESULTS:

Twenty-eight patients diagnosed with perioperative allergy were included. Main triggers were neuromuscular blocking agents (46.42 %), latex (28.52 %) and propofol (14.28 %). The main risk factor was a history of previous surgeries (89.28 %). Most perioperative allergic reactions were mild (71.42 %) and occurred within the postoperative period (60.71 %).

CONCLUSIONS:

Initial diagnosis and Treatment should always be carried out by the anesthesiologist or surgeon, who should focus on the withdrawal of possible causative agents.

KEYWORDS:

Anaphylaxis; Hypnotics; Latex; Local anesthetics; Neuromuscular blocking agents; Perioperative allergy

PMID:
30602208
DOI:
10.29262/ram.v65i4.513

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