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Rev Alerg Mex. 2018 Oct-Dec;65(4):362-371. doi: 10.29262/ram.v65i4.386.

[Evaluation of vitamin D serum levels in asthmatic adults and their relationship with asthma control].

[Article in Spanish; Abstract available in Spanish from the publisher]

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Universidad Autónoma de Nuevo León, Hospital Universitario Dr. José Eleuterio González, Centro Regional de Alergia e Inmunología Clínica, Monterrey, México.


in English, Spanish


Decreased levels of vitamin D influence on the control and severity of asthma.


To evaluate the relationship between vitamin D serum levels and asthma control, as well as nutritional status, quality of life and patient comorbidities.


Cross-sectional, observational, descriptive study of 43 asthmatic patients older than 18 years of age. Multiple logistic and multiple linear regression multivariate analyses of variance were performed; a p-value ≤ 0.05 was considered to be statistically significant.


Insufficient vitamin D levels were determined in 83.7 % of patients; 93 % had at least one asthma exacerbation in the previous year. There was no relationship between vitamin D serum levels and asthma control as measured by ACT and FEV1. There was a significant association between body mass index and vitamin D levels (p = 0.013). With a quality of life questionnaire for asthmatic adults, 76.7 % were recorded to have a poor quality of life.


No relationship was observed between vitamin D serum levels and asthma control in the patients. Most patients had insufficient vitamin D serum levels, uncontrolled asthma, and poor quality of life. Overweight and grade I obesity were associated with vitamin D insufficient levels.


Asthma; Asthma control test; Body mass index; Quality of life; Vitamin D


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