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Int J Appl Basic Med Res. 2018 Oct-Dec;8(4):269-271. doi: 10.4103/ijabmr.IJABMR_393_17.

Cerebral Aspergillosis Mimicking a Neoplasm in an Immunocompetent Patient.

Author information

1
Department of Radiodiagnosis, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
2
Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
3
Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Abstract

Cerebral aspergillosis mostly presents as single or multiple abscesses with vascular invasion in immunocompromised patients. A rare mass like or tumoral form of cerebral aspergillosis has been described mostly in immunocompetent patients. A 22-year-old-male presented with recurrent attacks of complex partial seizures with secondary generalization, headache, and blurring of vision. Preoperative diagnosis of a cerebral neoplasm was considered in view of solid mass-like enhancement. However, histopathological examination was suggestive of central nervous system aspergillosis. The presence of imaging findings such as T2 hypointensity, irregular frond-like margins, and absence of choline peak may be the clues, which suggest a fungal etiology.

KEYWORDS:

Aspergillosis; cerebral; magnetic resonance imaging; neoplasm

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