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Int J Appl Basic Med Res. 2018 Oct-Dec;8(4):253-255. doi: 10.4103/ijabmr.IJABMR_397_17.

Dermal Lymphatic Invasion: A Rare Feature in Benign Intradermal Nevus.

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Department of Pathology, Deen Dayal Upadhyay Hospital, New Delhi, India.


The present case describes classical intradermal nevus with intralymphatic nevus cell emboli. A 13-year-old boy presented with black colored macule on the shin 1 cm in diameter which was gradually increasing in size. Histopathology of the lesion was typical of an intradermal melanocytic nevus. The most notable feature of this case, however, was an occasional aggregate of nevus cells within a lymphatic vessel of the upper dermis. The nevus cells within lymphatic lumen had morphological features of type A nevus cells. The cells were roundtocuboidal, exhibited abundant cytoplasm with welldefined cell borders and formed nests. These nevus cell aggregates were surrounded by flattened endothelial cells. Due to its rarity, a lymphatic nevus cell embolus creates diagnostic issues for pathologists. This observation must not be interpreted as evidence of malignancy but significant as a rare histological feature. In other words, the nevus cells might have been transported through the lymphatic vessels as a "benign metastasis."


Intradermal nevus; intralymphatic nevus cell aggregates; intralymphatic nevus cell protrusion/projection; melanocytic precursor; pseudolymphatic

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