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Int J Appl Basic Med Res. 2018 Oct-Dec;8(4):227-230. doi: 10.4103/ijabmr.IJABMR_105_18.

Vitamin D Levels: Do We Need to Assess Only in Disease?

Author information

1
Department of Biochemistry, Centre for Interdisciplinary Biomedical Research, Adesh University, Bathinda, Punjab, India.
2
Department of Biochemistry, AIMSR, Adesh University, Bathinda, Punjab, India.
3
Department of Community Medicine, AIMSR, Adesh University, Bathinda, Punjab, India.

Abstract

Background:

Vitamin D is conventionally known as sunshine vitamin and is synthesized endogenously in sunlight. Vitamin D is known to be a key regulator of bone metabolism, the function of genes, and essential for the development of the whole body. Deficiency of Vitamin D is now become a major worldwide epidemic health problem.

Aim:

The present study was conducted with the objective of determining the prevalence of Vitamin D deficiency (VDD) in urban population of a district in south Punjab, across various characteristics of population such as gender, age, and socioeconomic status.

Materials and Methods:

A cross-sectional population survey was conducted in the urban population of the district. A total of 120 healthy volunteers of either sex participated and their 25-hydroxy Vitamin D concentrations in serum samples were estimated using ELISA. The participants were divided into three categories as follows: Vitamin D deficient, insufficient, or sufficient, on the basis of normal standardized serum levels of Vitamin D <20, 20-30, and >30 ng/ml, respectively.

Results:

Of 120 healthy individuals, 95% of the study participants had VDD or insufficiency and only 5% had adequate Vitamin D levels. In each age group, females showed lower Vitamin D levels as compared to males. Furthermore, high body mass index value was associated with low Vitamin D. Upper-class individuals also showed low levels of Vitamin D as compared to other socioeconomic classes' individuals.

Conclusions:

Overall, high prevalence of VDD among the apparently healthy urban population of the district was observed and gives an alarming sign about continuously increasing prevalence of hypovitaminosis D among healthy population.

KEYWORDS:

25 (hydroxycholecalciferol) D; Vitamin D; body mass index; deficiency; prevalence

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