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Indoor Air. 2019 Mar;29(2):202-214. doi: 10.1111/ina.12534. Epub 2019 Jan 22.

Household renovation before and during pregnancy in relation to preterm birth and low birthweight in China.

Author information

1
Department of Building Science, Tsinghua University, Beijing, China.
2
Beijing Key Laboratory of Indoor Air Quality Evaluation and Control, Tsinghua University, Beijing, China.
3
School of Environment and Architecture, University of Shanghai for Science and Technology, Shanghai, China.
4
Joint International Research Laboratory of Green Buildings and Built Environments (Ministry of Education), Chongqing University, Chongqing, China.
5
Department of Environmental Health, School of Public Health, Fudan University, Shanghai, China.
6
College of Life Sciences, Central China Normal University, Wuhan, China.
7
School of Energy Science and Engineering, Central South University, Changsha, China.
8
Research Center for Environmental Science and Engineering, Shanxi University, Taiyuan, China.
9
School of Energy and Environment, Southeast University, Nanjing, China.
10
School of Environmental Science and Technology, Tianjin University, Tianjin, China.
11
China Meteorological Administration Training Centre, China Meteorological Administration, Beijing, China.
12
School of Energy and Environment, Inner Mongolia University of Science and Technology, Baotou, China.
13
Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden.

Abstract

From October 2010 to April 2012, we conducted a cross-sectional study of associations between household environments and childhood health among preschool children in eight Chinese cities. Here, we analyze associations of early household renovation with preterm birth (PTB), low birthweight (LBW), term low birthweight (Term-LBW), and small for gestational age (SGA). Parents responded to questions about household renovation and their children's gestational age and birthweight. In the multivariate logistic regression analyses, household renovation in the year before pregnancy was significantly associated with LBW (sample size: N = 25 813; adjusted odds ratio (OR) with 95% confidence intervals (CIs): 1.23, 1.01-1.50) and Term-LBW (N = 24 823; 1.29, 1.01-1.67). Household renovation during pregnancy was significantly associated with PTB (N = 25 202; 1.28, 1.01-1.69). These significant associations were also found in the two-level (city-child) logistic regression analyses and in the sensitivity analyses among 21 009 children with complete data in all studied variates. Stronger associations were found in certain subgroups. Our findings indicate that household renovation within one year before pregnancy might be a risk factor for LBW and Term-LBW, while household renovation during pregnancy could be a risk factor for PTB.

KEYWORDS:

China; home renovation; low birthweight; prenatal exposure; preterm birth

PMID:
30597644
DOI:
10.1111/ina.12534

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