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JAMA Pediatr. 2019 Feb 1;173(2):183-184. doi: 10.1001/jamapediatrics.2018.4575.

Probiotics for Children With Recurrent Abdominal Pain.

Author information

University of Exeter Medical School, Exeter, England.
National Institute for Health Research Collaborations for Leadership in Applied Health Research and Care South West Peninsula, University of Exeter Medical School, Exeter, England.
Bristol Royal Hospital for Children, Bristol, England.


Clinical Question:

Do dietary interventions, such as probiotics, improve pain in children with recurrent abdominal pain?

Clinical Application:

Compared with placebo, children who were treated with probiotic preparations were more likely to experience improvement in pain in the short term (odds ratio, 1.63; 95% CI, 1.07-2.47), suggesting that clinicians could consider probiotics as part of a holistic management strategy in recurrent abdominal pain.

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