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J Cancer Res Ther. 2018;14(7):1578-1582. doi: 10.4103/jcrt.JCRT_210_18.

Diagnosis and treatment of hemangiopericytoma in the central nervous system.

Author information

1
Department of Radiation Oncology, Chinese PLA General Hospital, Beijing, China.
2
Department of Radiation Oncology, First Affiliated Hospital of PLA General Hospital, Beijing, China.

Abstract

Objective:

This study aimed to explore the clinical characteristics and treatment of the hemangiopericytoma (HPC) in the central nervous system.

Materials and Methods:

Clinical data from 14 patients with HPC in the central nervous system who were followed up for 12-107 months were retrospectively analyzed, and relevant literature was reviewed.

Results:

All 14 patients underwent surgery and postoperative pathologic diagnosis, including 8 cases of total excision, 3 cases of subtotal excision, and 3 cases of partial excision. There were 7 recurrent cases (50%, 4 cases of total excision, 1 case of subtotal excision, and 2 cases of partial excision, none of them received postoperative radiotherapy) with a median relapse time of 39 months, where the median relapse time after total excision was 41.5 months, and after nontotal excision was 17 months. In addition, patients could survive for a long time after reoperation following relapse and after receiving postoperative radiotherapy.

Conclusion:

The diagnosis of HPC depends on the pathology. Currently, the surgery and postoperative radiotherapy provide a good treatment results, while the wholeness of surgical resection is of particular importance.

KEYWORDS:

Central nervous system; clinical features; hemangiopericytoma; radiotherapy

PMID:
30589042
DOI:
10.4103/jcrt.JCRT_210_18
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