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Ann Med Surg (Lond). 2018 Dec 4;37:30-37. doi: 10.1016/j.amsu.2018.11.009. eCollection 2019 Jan.

Evaluate the effects of platelet rich plasma (PRP) and zinc oxide ointment on skin wound healing.

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Sulaimani Veterinary Directorate, Veterinary Quarantine, Sulaimani International Airport, Iraq.
University of Van Yȕzȕncȕ Yıl, Veterinary College, Department of Surgery, Van, Turkey.
Sulaimani Veterinary Directorate, Veterinary Quarantine, Bashmakh International Border, Iraq.


In this study efficiency of platelet rich plasma (PRP) and zinc oxide on full thickness wounds created on rabbits was researched. This study conducted on 24 New Zealand rabbits divided 2 groups. A circular of 1.5 × 1.5 cm (2.5 cm2) full thickness skin wound was created under the general anesthesia. 1 ml PRP (5.503106/mm3) was applied to the one of the wounds subcutaneously. To the other wound 1 mm3 zinc oxide ointment was applied once a day during the study. Wound contraction rates were measured, biopsy materials were collected and evaluated macroscopically and histopathologically postoperatively 3rd, 7th and 15th days. As a result it is determined that PRP and zinc oxide accelerated wound contraction rates between the groups were determined as 3rd day p = 0.007, 7th day p = 0.0002 and 15th day p = 0.002.


Inflammation; Platelet rich plasma; Rabbits; Skin wound healing; Zinc oxide

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