Format

Send to

Choose Destination
Genome Med. 2018 Dec 21;10(1):98. doi: 10.1186/s13073-018-0609-3.

Emerging evidence linking the gut microbiome to neurologic disorders.

Author information

1
Division of Biology and Biological Engineering, California Institute of Technology, East California Boulevard, Pasadena, CA, 91125, USA. jgriffit@caltech.edu.
2
Division of Biology and Biological Engineering, California Institute of Technology, East California Boulevard, Pasadena, CA, 91125, USA. sarkis@caltech.edu.

Abstract

The gut microbiome contributes to the development and function of the immune, metabolic, and nervous systems. Furthermore, commensal bacteria modulate symptoms and pathology in mouse models of neuropsychiatric and neurodevelopmental diseases. Uncovering mechanisms that are utilized by the microbiome to mediate gut-brain connections may provide novel opportunities to target therapies to the gut in order to treat neurologic disorders.

Supplemental Content

Full text links

Icon for BioMed Central Icon for PubMed Central
Loading ...
Support Center