[Salvia officinalis Reduces the Severity of the Premenstrual Syndrome]

Complement Med Res. 2019;26(1):39-46. doi: 10.1159/000490104. Epub 2018 Dec 15.
[Article in German]

Abstract

Background: This study aims to investigate the effects of Salvia officinalis on the severity of the premenstrual syndrome (PMS).

Methods: This was a triple-blinded randomized clinical trial on 90 college students in Tehran, Iran. The participants were randomly divided into 2 groups who were treated with 500-mg Salvia officinalis capsules or placebo once a day for 2 consecutive months. Data were collected using a questionnaire and a daily form for recording symptoms of PMS.

Results: The mean decreases in severity of the symptoms in the Salvia officinalis extract-treated group during the first and second months after treatment were 19.84% and 23.42%, respectively. The comparison of the PMS physical and psychological symptoms demonstrated a decrease following treatment in both groups, with more remarkable reduction in the Salvia officinalis group (p < 0.001).

Conclusion: Salvia officinalis is an effective alternative agent to reduce the severity of psychological and physical symptoms of PMS.

Keywords: Salvia officinalis extract; Clinical trial; Placebo; Premenstrual syndrome.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Female
  • Humans
  • Iran
  • Phytotherapy*
  • Premenstrual Syndrome / therapy*
  • Salvia officinalis*
  • Surveys and Questionnaires
  • Treatment Outcome