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Cureus. 2018 Oct 16;10(10):e3457. doi: 10.7759/cureus.3457.

Resolution of a Greater Than 50-year History of Severe, Chronic Low Back Pain Following an Ultrasound-guided Platelet-rich Plasma Infiltration of the Thoracolumbar Fascia.

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Physical Medicine and Rehabilitation, New York University / Langone Medical Center, New York, USA.


The diagnosis of chronic low back pain is a scourge of society that does not take into account the pathoanatomical cause of pain. This case describes a six-year search for the pinpoint pathoanatomical diagnosis of a patient's 50-plus year history of debilitating chronic low back pain after he failed the standard nonoperative and operative treatment modalities. Ultrasound-guided diagnostic blocks identified a potential space within the thoracolumbar fascia. This was treated with platelet-rich plasma, yielding a complete resolution of his pain and a full return to normal activities of daily living for three years since the procedure.


chronic back pain; fascia; low back pain; lumbar pain; lumbar spine; musculoskeletal symptoms; musculoskeletal ultrasound; pain management; platelet-rich plasma; ultrasound

Conflict of interest statement

The authors have declared that no competing interests exist.

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