Hemophagocytic lymphohistiocytosis in the setting of HELLP Syndrome

Sarmen Sarkissian; Yasir Khan; Daniel Farrell; David Constable; Elizabeth Brem

doi:10.1002/ccr3.1828

Hemophagocytic lymphohistiocytosis in the setting of HELLP Syndrome

Clin Case Rep. 2018 Nov 5;6(12):2466-2470. doi: 10.1002/ccr3.1828. eCollection 2018 Dec.

Authors

Sarmen Sarkissian¹, Yasir Khan², Daniel Farrell³, David Constable⁴, Elizabeth Brem²

Affiliations

¹ Pacific Shoes Medical Group Long Beach California.
² Division of Hematology and Oncology, Department of Medicine University of California, Irvine Irvine California.
³ Department of Pathology University of California, Irvine Irvine California.
⁴ Division of Infectious Disease, Department of Medicine University of California, Irvine Irvine California.

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyper activation of the immune system. Rare cases associated with HELLP syndrome and other similar conditions in pregnancy have been reported. Despite the improved survival rates with etoposide and dexamethasone-based regimens, HLH remains a challenging disease. Experience in pregnant patients is exceedingly rare.

Keywords: EBV; HELLP syndrome; hemophagocytic lymphohistiocytosis; hemophagocytosis.

Publication types

Case Reports