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Curr Biol. 2018 Dec 17;28(24):R1403-R1405. doi: 10.1016/j.cub.2018.11.003.

Signal Transduction: Magnesium Manifests as a Second Messenger.

Author information

1
MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
2
MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK. Electronic address: oneillj@mrc-lmb.cam.ac.uk.

Abstract

Mg2+ is an essential ion for the cell but whether it can act as a bona fide second messenger has long been questioned. A recent study supports this hypothesis and shows a signalling role for Mg2+ in GABA-mediated neuronal maturation.

PMID:
30562536
DOI:
10.1016/j.cub.2018.11.003
[Indexed for MEDLINE]

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