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Emerg Infect Dis. 2019 Jan;25(1):157-160. doi: 10.3201/eid2501.171862.

Surgical Site Infections Caused by Highly Virulent Methicillin-Resistant Staphylococcus aureus Sequence Type 398, China.


We identified 2 methicillin-resistant Staphylococcus aureus strains of sequence type 398 from surgical site infections in China. Genetic analysis and clinical data from these strains suggested that they were human-related but sporadic. Hemolysis analysis and mouse-skin infection models indicated a high virulence potential for these strains.


China; MRSA; MRSA and other staphylococci; ST398; antimicrobial resistance; bacteria; core genome MLST; methicillin-resistant Staphylococcus aureus; surgical site infection; virulence

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