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Mayo Clin Proc Innov Qual Outcomes. 2018 Oct 25;2(4):398-401. doi: 10.1016/j.mayocpiqo.2018.09.003. eCollection 2018 Dec.

Lyme Disease-An Unusual Cause of a Mitral Valve Endocarditis.

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Department of Cardiovascular Surgery, Mayo Clinic, Rochester, MN.
Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, MN.


Lyme disease is a tick-borne infection caused by Borrelia burgdorferi. Cardiac manifestations are rare, occurring in 0.5% to 10% of patients. Lyme carditis and atrioventricular block are established manifestations of Lyme disease. Endocarditis caused by Borrelia has been reported only twice previously, and in both cases, these were species (Borrelia afzelii and Borrelia bissettii) not present in North America. We report a unique case of mitral valve endocarditis caused by B burgdorferi.


AML, anterior mitral valve leaflet; ELISA, enzyme-linked immunosorbent assay; MR, mitral regurgitation; PCR, polymerase chain reaction; TEE, transesophageal echocardiography

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