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Head Neck. 2019 May;41(5):1206-1212. doi: 10.1002/hed.25538. Epub 2018 Dec 14.

Diagnostic value of computed tomography combined with ultrasonography in detecting cervical recurrence in patients with thyroid cancer.

Author information

1
Department of Radiology, Seoul National University Hospital, Seoul, Republic of Korea.
2
Department of Radiology, Seoul National University College of Medicine, Seoul, Republic of Korea.
3
Division of Clinical Epidemiology, Medical Research Collaborating Center, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.
4
Department of Radiology, Gangnam Center, Seoul National University Hospital Healthcare System, Seoul, Republic of Korea.
5
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
6
Department of Otorhinolaryngology, Seoul National University College of Medicine, Seoul, Republic of Korea.
7
Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea.

Abstract

BACKGROUND:

To determine the diagnostic role of CT added to ultrasound for the diagnosis of recurrent differentiated thyroid cancer (DTC) and to evaluate potential benefits for patients.

METHODS:

A total of 193 patients with recurrent DTC were retrospectively included. The diagnostic performances of ultrasound and combination of ultrasound and CT (ultrasound/CT) in detecting recurrence were compared. Benefits of CT were assessed based on the presence of any recurrence detected only with additional CT.

RESULTS:

In detecting cervical recurrence, ultrasound/CT showed higher sensitivity (P = .001) and lower specificity (P < .001) than ultrasound alone, overall resulting in higher area under the curve (P < .001). Seventy-nine patients (40.9%) benefited from additional CT in detecting recurrence.

CONCLUSION:

For reoperation of cervical recurrence in patients with DTC, addition of CT to ultrasound offers better surgical planning by enhancing detection of recurrent cancers that were overlooked with ultrasound alone.

KEYWORDS:

recurrence; thyroid gland; thyroid neoplasms; tomography; ultrasonography

PMID:
30552732
DOI:
10.1002/hed.25538

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