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Laryngoscope. 2019 Nov;129(11):E402-E406. doi: 10.1002/lary.27723. Epub 2018 Dec 13.

Hypoglossal nerve stimulation in three adults with down syndrome and severe obstructive sleep apnea.

Author information

1
Department of Otolaryngology-Head and Neck Surgery, Weill Cornell Medicine, New York, New York.
2
Department of Otolaryngology-Head and Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania.
3
Divisions of Pediatric Otolaryngology-Head and Neck Surgery and Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
4
Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, U.S.A.

Abstract

We present three adults with Down syndrome and obstructive sleep apnea (OSA) treated with hypoglossal nerve stimulation. The average age of these three males was 37.3 years. All patients had severe OSA on polysomnography. Postimplantation titration sleep studies exhibited residual OSA according to average total apnea-hypopnea index (AHI), but there were significant reductions (86%-100%) in the titrated AHI at the ideal device setting. Morbidity of the surgery was low, and there was excellent device adherence, with an average of 57.3 hours/week. All patients reported subjective improvements in symptoms, and one patient experienced improved blood sugar control. Laryngoscope, 129:E402-E406, 2019.

KEYWORDS:

Down syndrome; Hypoglossal nerve stimulation; obstructive sleep apnea; upper airway stimulation

PMID:
30549045
DOI:
10.1002/lary.27723
[Indexed for MEDLINE]

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