Format

Send to

Choose Destination
Indian J Public Health. 2018 Oct-Dec;62(4):287-293. doi: 10.4103/ijph.IJPH_313_17.

Effect of directly observed oral iron supplementation during pregnancy on iron status in a rural population in Haryana: A randomized controlled trial.

Author information

1
Senior Resident, Centre for Community Medicine, All India Institute of Medical Sciences, New Delhi, India.
2
Associate Professor, Centre for Community Medicine, All India Institute of Medical Sciences, New Delhi, India.
3
Professor and Head, Centre for Community Medicine, All India Institute of Medical Sciences, New Delhi, India.
4
Professor and Head, Department of Hematology, All India Institute of Medical Sciences, New Delhi, India.
5
Associate professor, Public Health, IIHMR University, Jaipur, Rajasthan, India.
6
Professor and Former Head, Centre for Community Medicine, All India Institute of Medical Sciences, New Delhi, India.

Abstract

Background:

In India, more than half of the pregnant women suffer from anemia. Low compliance to iron supplementation is one of the important reasons.

Objectives:

The objective of the study is to estimate the reduction in the prevalence of anemia, improvement in iron status, and to compare the compliance to oral iron supplementation during pregnancy between directly observed iron-folic acid (IFA) supplementation group and control group.

Methods:

This was a community-based open labeled parallel block-randomized controlled trial including 400 pregnant women in a rural setting of north India. In the intervention group, the first dose of IFA every week was supervised by ASHA and women were instructed to take the remaining tablets during the week as per the prescription. In control group, IFA tablets were supplemented without direct supervision.

Results:

After 100 days of IFA supplementation, the reduction in anemia in the intervention group was 6% higher as compared to control group (P = 0.219). The increase in the mean hemoglobin level over and above control group was 0.52 g/dl in intervention group (P < 0.001). However, the mean increase in serum ferritin level in the intervention group was similar to the control group. The mean percentage compliance in the intervention group was almost 9% higher than that of control group (P = 0.001).

Conclusion:

Directly supervised oral iron (IFA) supplementation improves compliance to oral iron (IFA) supplementation and also improves hemoglobin status among pregnant women. However, the mean increase in serum ferritin and reduction in the prevalence of anemia in the intervention group were not higher than the control group.

KEYWORDS:

Anemia prevalence; compliance; directly observed; iron-folic acid; oral iron supplementation; pregnant women

PMID:
30539891
DOI:
10.4103/ijph.IJPH_313_17
Free full text

Supplemental Content

Full text links

Icon for Medknow Publications and Media Pvt Ltd
Loading ...
Support Center