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J Pediatr Adolesc Gynecol. 2019 Apr;32(2):103-109. doi: 10.1016/j.jpag.2018.11.007. Epub 2018 Dec 5.

Challenges and Opportunities in Adolescent Gynecology Patients with Surgically-Treated Congenital and Acquired Anomalies: Transition of Care from Pediatric to Adult Surgery.

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Norton Children's Hospital, University of Louisville, Louisville, KY. Electronic address:
John R Oishei Hospital, University of Buffalo, Buffalo, NY.


The transition from adolescence to young adulthood in patients with reproductive health care needs such as disorders of sexual development and congenital anomalies is a complex process that occurs over several years. The transition process for these patients is still poorly understood. The patients with disorders of sexual development and reproductive issues have specific and unique issues regarding timing of disclosure of diagnosis, genital examinations, gonadectomy, vaginal treatments, surgical procedures, hormone replacement therapy, use of long-term medication, and potential cancer screening. The purpose of this review is to briefly describe complex genital malformations and their associated anomalies with long-term concerns and then provide an overview of what has been published at this time regarding the transition of care to provide some guidance for providers who care for those patients.


Adolescents; Congenital adrenal hyperplasia; DSD; Disorders of sexual development; Gynecologic anomalies; Intersex; MRKH syndrome; Ovarian conditions; Transition of care; Uterovaginal agenesis

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