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Trends Parasitol. 2019 Jan;35(1):72-84. doi: 10.1016/j.pt.2018.09.010. Epub 2018 Oct 24.

Transcriptomic Resources for Parasitic Nematodes of Veterinary Importance.

Author information

1
Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Melbourne, Victoria, Australia; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. Electronic address: jex.a@wehi.edu.au.
2
Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Melbourne, Victoria, Australia.
3
Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Melbourne, Victoria, Australia; Cornell University, Ithaca, NY 14850, USA.

Abstract

Parasitic nematodes are important pathogens of animals, causing diseases that impact on agricultural production worldwide. Research on these worms has been constrained by a lack of genetic and genomic tools. Nonetheless, over the past decade this field has made substantial advances, many of which have been led by transcriptomic sequencing. The present review summarises major transcriptomic studies of veterinary parasitic nematodes in recent years, and comments on overarching themes stemming from this work that inform our understanding of parasitism. Finally, we comment on current, state-of-the-art informatic tools for the analysis of complex worm transcriptomes to extract maximum the molecular information from them.

KEYWORDS:

RNA sequencing; transcriptomics; veterinary nematode

PMID:
30529253
DOI:
10.1016/j.pt.2018.09.010
[Indexed for MEDLINE]

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