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Med Sci (Paris). 2018 Nov;34(11):936-943. doi: 10.1051/medsci/2018239. Epub 2018 Dec 10.

[Extracellular vesicles as biomarkers and bioeffectors of metabolic syndrome].

[Article in French]

Author information

1
UMR Inserm 1063 « Stress oxydant et pathologies métaboliques », Institut de Biologie en Santé - IRIS, 4 rue Larrey, Angers, France.
2
UMR Inserm 1063 « Stress oxydant et pathologies métaboliques », Institut de Biologie en Santé - IRIS, 4 rue Larrey, Angers, France - Centre hospitalo-universitarire d'Angers, 4 rue Larrey, Angers, France.

Abstract

Extracellular vesicles (EVs) are emerging as a novel way of cell-to-cell communication and represent an attractive way to convey fundamental information between cells. EVs, released in the extracellular space, circulate via the various body fluids and modulate locally or remotely the cellular responses following their interaction with the target cells. Clinical and experimental data support their role as biomarkers and bioeffectors in diseases related to the metabolic syndrome. EVs thus hustle the traditional vision of intercellular communication, via an alternative and versatile mode of communication, and open the door to new concepts and opportunities from a therapeutic and biological point of view.

PMID:
30526838
DOI:
10.1051/medsci/2018239

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