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Rev Med Inst Mex Seguro Soc. 2018 Nov 30;56(4):342-346.

Variability of arterial and peripheral venous blood gases parameters in subjects with stable obstructive pulmonary disease

[Article in Spanish; Abstract available in Spanish from the publisher]

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Instituto Mexicano del Seguro Social, Hospital de Cardiología, Departamento de Hipertensión Pulmonar y Corazón Derecho. Ciudad de México, México


in English, Spanish


Peripheral venous blood gases may be useful in subjects with exacerbation of chronic obstructive pulmonary disease to evaluate their gas exchange.


To describe the variability of parameters of arterial and peripheral venous blood gases in subjects with stable obstructive pulmonary disease.


Cross-sectional design, consecutive subjects were studied in a blinded manner, while arterial and peripheral venous blood was obtained for analysis. Variability was established with Bland-Altman statistical method and its magnitude with the intraclass correlation coefficient (95 % confidence interval).


Three hundred blood samples from 150 patients were studied, 89 (59.3%) women, age 66 ± 10 years old, body mass index 28.44 ± 4.81 Kg/m2. Mean difference (bias) [intraclass correlation coeficient] pH 0.012 (-0.009, 0.032) [0.927], Carbon dioxide pressure -6.5 (-14.1, 1.1) [ 0.643], serum bicarbonate -1.3 (-3.3, 0.7) [0.929], base excess -1 (-4, 2.1) [0.904], hemoglobin -0.1 (-1.9, 1.8) [0.947].


The variability of pH, serum bicarbonate, and hemoglobin are similar in both blood samples. These arterial or peripheral venous blood gas parameters could be used interchangeably.


Reproducibility of Results; Epidemiologic Studies; Blood Gas Analysis; Bias


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