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Rev Med Inst Mex Seguro Soc. 2018 Nov 30;56(4):424-428.

Breast cancer in males, case presentation and literature review

[Article in Spanish; Abstract available in Spanish from the publisher]

Author information

Instituto de Seguridad Social del Estado de México y Municipios, Centro Médico ISSEMyM Ecatepec, Servicio de Cirugía General. Ecatepec, Estado de México, México


in English, Spanish


Male breast cancer is a rare entity, with an approximate rate of 1.1 / 100 000 in the US, with an average age of 67 years. In all cases a genetic study must be performed, in order to find mutations in known genes, and after the resolution of the disease, based on the results, a contralateral prophylactic mastectomy should be considered.

Clinical case:

53 -year-old male diagnosed with right breast cancer, infiltrating ductal adenocarcinoma type, clinical stage IIB, breast cancer on 2 immediate family history, mutations of the BRCA1 gene and positive hormone receptors and Her2/Neu. He was treated with modified radical mastectomy in diseased side with subsequent neoadjuvant chemotherapy/radiotherapy. After a year of follow-up and a free behavior of disease, contralateral prophylactic mastectomy was performed. The patient progressed satisfactorily, following up to 18 months since the beginning, with no tumor activity data.


Breast cancer in male patient has a worse prognosis than female patients, due to lower amount of tissue in breast exposed to an earlier chest spread and a different biological behavior, also a higher risk of prostate and pancreatic cancer is associated. Studies of adequate methodological quality are scarce, so that decisions are based on guidelines for breast cancer in women.


Breast Neoplasms; Male; Genes, BRCA1; Mastectomy


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