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Environ Sci Pollut Res Int. 2019 Jan;26(3):2238-2252. doi: 10.1007/s11356-018-3796-y. Epub 2018 Dec 6.

Chronic mercury exposure and blood pressure in children and adolescents: a systematic review.

Author information

1
Conselleria de Sanitat Universal i Salut Pública, Generalitat Valenciana, Valencia, Spain.
2
FISABIO-UJI-Universitat de València Joint Research Unit in Epidemiology and Environmental Health, Valencia, Spain.
3
Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Madrid, Spain.
4
Nursing Department, University of Valencia, Valencia, Spain.
5
FISABIO-UJI-Universitat de València Joint Research Unit in Epidemiology and Environmental Health, Valencia, Spain. llop_sab@gva.es.
6
Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Madrid, Spain. llop_sab@gva.es.
7
Foundation for the Promotion of Health and Biomedical Research in the Valencian Region, FISABIO-Public Health, Avda. Catalunya 21, 46020, Valencia, Spain. llop_sab@gva.es.

Abstract

The aim of this paper is to systematically review the scientific literature on the possible relation of chronic mercury exposure and blood pressure among children and adolescents. We searched for observational studies in 6 electronic databases and grey literature for English, French or Spanish language studies published up to 30th November 2017. We performed a quality assessment of primary studies. We identified 8 articles involving 5 cohorts, 1 cross-sectional study and 1 case-control study. The participants had mean ages of between 3 and 17 years. Mercury was analysed in different matrices and periods of exposure. Four articles evaluated prenatal exposure, 2 evaluated both prenatal and postnatal exposures and 2 postnatal exposure. Blood pressure was measured according to different protocols. The association between mercury and blood pressure was adjusted by different covariates in each study. Four articles found a positive significant association between chronic mercury exposure and blood pressure in children or adolescents. Among these 4 articles, three of them evaluated prenatal exposure. There are still few studies assessing chronic mercury exposure and blood pressure in children and adolescents with inconsistency in results. Designs are very heterogeneous, which hampers their comparability. Evidence of this association is scarce and further research is needed.

KEYWORDS:

Blood pressure; Cardiovascular; Environmental exposure; Epidemiology; Mercury; Paediatrics; Public health

PMID:
30519915
DOI:
10.1007/s11356-018-3796-y
[Indexed for MEDLINE]

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