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J Virus Erad. 2018 Nov 15;4(Suppl 2):5-8.

The contribution of observational studies in supporting the WHO 'treat all' recommendation for HIV/AIDS.

Author information

1
Department of HIV and Global Hepatitis Programme, WHO, Geneva, Switzerland.
2
Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, South Africa.
3
Institute of Social and Preventive Medicine, University of Bern, Switzerland.

Abstract

In 2015, the World Health Organization (WHO) recommended that all people living with HIV (PLWH) should start antiretroviral therapy (ART) irrespective of clinical or immune status. This recommendation followed almost 20 years of research into the clinical and population-level benefits and risks of starting ART early compared with deferring treatment. This article summarises the ways in which observational data support the work of WHO, including the support provided by the International epidemiology Databases to Evaluate AIDS (IeDEA), taking the example of 'treat all'.

PMID:
30515308
PMCID:
PMC6248853

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