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J Am Coll Nutr. 2019 Jan;38(1):1-14. doi: 10.1080/07315724.2018.1500499. Epub 2018 Dec 4.

Personalized Nutrition in Disrupting Cancer - Proceedings From the 2017 American College of Nutrition Annual Meeting.

Author information

a Department of Nutrition and Food Studies , George Mason University , Fairfax, VA , USA.
b Think Healthy Group, Inc , Washington, DC , USA.
c Department of Genetics, University of North Carolina School of Medicine.
d Departments of Family and Community Medicine and Epidemiology and Public Health , Center for Integrative Medicine, University of Maryland School of Medicine.
e Department of Epidemiology, Division of Cancer Prevention and Population Sciences , The University of Texas MD Anderson Cancer Center.
f Department of Medical Epidemiology and Biostatistics , Karolinska Institute , Stockholm , Sweden.
g Moore Family Center for Whole Grain Foods, Nutrition and Preventive Health, School of Biological and Population Health Sciences, Linus Pauling Institute, Oregon State University.
h Channing Division of Network Medicine , Brigham and Women's Hospital and Harvard Medical School.
i Harvard T.H. Chan School of Public Health.
j Department of Medicine , University of Arizona , Tucson.
k National Institute of Integrative Medicine , Melbourne , Australia.
l Oregon Integrative Oncology , Ashland , Oregon.
m Department of Biology , Boston College.
n Institute for Systems Biology, P4 Medicine Institute.
o Weill Cornell Breast Center, Weill Cornell Medicine.


Cancer is a major public health problem and is the second leading cause of death in the United States and worldwide; nearly one in six deaths are attributable to cancer. Approximately 20% of all cancers diagnosed in the United States are attributable to unhealthy diet, excessive alcohol consumption, physical inactivity, and body fatness. Individual cancers are distinct disease states that are multifactorial in their causation, making them exceedingly cumbersome to study from a nutrition standpoint. Genetic influences are a major piece of the puzzle and personalized nutrition is likely to be most effective in disrupting cancer during all stages. Increasing evidence shows that after a cancer diagnosis, continuing standard dietary recommendations may not be appropriate. This is because powerful dietary interventions such as short-term fasting and carbohydrate restriction can disrupt tumor metabolism, synergizing with standard therapies such as radiation and drug therapy to improve efficacy and ultimately, cancer survival. The importance of identifying dietary interventions cannot be overstated, and the American College of Nutrition's commitment to advancing knowledge and research is evidenced by dedication of the 2017 ACN Annual Meeting to "Disrupting Cancer: The Role of Personalized Nutrition" and this resulting proceedings manuscript, which summarizes the meeting's findings.


American College of Nutrition; Cancer; nutrition; scientific statement

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