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J Oral Pathol Med. 2018 Dec 3. doi: 10.1111/jop.12810. [Epub ahead of print]

Electronic nicotine delivery systems: Oral health implications and oral cancer risk.

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Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland, Baltimore, Maryland.
Australian Centre for Oral Oncology Research & Education, UWA Dental School, University of Western Australia, Nedlands, Western Australia, Australia.


There is a paucity of evidence surrounding the potential detrimental effects of electronic nicotine delivery systems (ENDS) for both systemic and oral health. The effects of conventional cigarettes on the development of oral cancer are well known; however, the role of ENDS in oral carcinogenesis is yet to be elucidated. Furthermore, the exponential rise of the use of ENDS by the general public means that dental healthcare providers are more likely to encounter questions on their safety in the oral cavity, and on their effectiveness as a smoking cessation aid. Herein, we review the most up to date literature on the systemic and oral health complications of ENDS. Moreover, evidence-based recommendations on the use of ENDS as a smoking cessation tool within the dental setting are discussed.


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