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Obstet Gynecol. 1988 Nov;72(5 Suppl):23S-30S.

The effects of postmenopausal estrogen therapy on the incidence of arteriosclerotic vascular disease.

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Department of Medicine, University of Washington School of Medicine, Seattle.


Recent studies show that arteriosclerotic cardiovascular disease is associated with high low-density lipoprotein and low high-density lipoprotein cholesterol concentrations and, further, that reversal of these abnormalities can prevent cardiovascular disease. As postmenopausal estrogen therapy favorably changes low-density lipoprotein and high-density lipoprotein cholesterol concentrations, it is hypothesized that reductions in cardiovascular disease will be observed in postmenopausal women so treated. The majority of at least 23 studies support this view.

[Indexed for MEDLINE]

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