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Neurol India. 2018 Nov-Dec;66(6):1550-1571. doi: 10.4103/0028-3886.246224.

Tuberculous meningitis: Challenges in diagnosis and management: Lessons learnt from Prof. Dastur's article published in 1970.

Author information

1
Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
2
Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
3
Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Abstract

It has been approximately five decades since Dastur et al., published their seminal work on pathology of tuberculous meningitis (TBM). Though most of their findings find relevance in today's era, there is an important difference; these findings can now be replicated during life using modern day technology. In this article, we review the seminal words of Professor Dastur and colleagues, analyse their findings, interpret how these revolutionized our understanding of TBM and highlight their relevance in today's era. We also discuss challenges in the management of TBM, which we continue to face today and the various options required to overcome these challenges.

KEYWORDS:

Antituberculous treatment; challenges; complication; tuberculosis; tuberculous meningitis

PMID:
30504541
DOI:
10.4103/0028-3886.246224
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Conflict of interest statement

Authors declare that they do not have any conflict of interest. They do not have any source of funding

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