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J Pediatr Hematol Oncol. 2018 Nov 28. doi: 10.1097/MPH.0000000000001363. [Epub ahead of print]

Disease Self-Efficacy and Health-Related Quality of Life in Adolescents With Sickle Cell Disease.

Author information

1
Division of Pediatric Psychology and Neuropsychology, Nationwide Children's Hospital.
2
Department of Pediatrics, The Ohio State University, Columbus.
3
Division of Behavioral Medicine.
4
Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.
5
Division of Hematology, Cincinnati Children's Hospital Medical Center.

Abstract

Adolescents and young adults (AYA) with sickle cell disease (SCD) are at risk for poor health-related quality of life (HRQOL). Research suggests that vulnerability factors (eg, disease severity) and self-management resources (eg, disease self-efficacy) jointly impact health outcomes, including HRQOL; however, this has not been studied among AYA with SCD. This study examined the relationship between disease self-efficacy, HRQOL, and disease severity in AYA with SCD. HRQOL was positively correlated with disease self-efficacy and negatively correlated with disease severity. Disease self-efficacy and severity accounted for 35% of variance in HRQOL. Findings support the impact of disease self-efficacy on HRQOL.

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