Send to

Choose Destination
Trends Neurosci. 2019 Feb;42(2):92-101. doi: 10.1016/j.tins.2018.10.004. Epub 2018 Oct 25.

Toward a Model of Interpersonal Trust Drawn from Neuroscience, Psychology, and Economics.

Author information

School of Systems Biology, George Mason University, Fairfax, VA, USA. Electronic address:
Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany.


Trust pervades nearly every social aspect of our daily lives, and its disruption is a significant factor in mental illness. Research in the field of neuroeconomics has gained a deeper understanding of the neuropsychoeconomic (NPE) underpinnings of trust by combining complementary methodologies from neuroscience, psychology, and economics. However, a coherent model of trust that integrates separate findings under a conceptual framework is still lacking. Here, we sketch out an integrative NPE model that explains how the interactions of psychoeconomic components engage domain-general large-scale brain networks in shaping trust behavior over time. We also point out caveats of current research approaches and outline open questions that can help guide future transdisciplinary investigations for a better understanding of the neuropsychology of trust.


bounded rationality; neuropsychoeconomics; social dilemma


Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center