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Chin Med. 2018 Nov 16;13:57. doi: 10.1186/s13020-018-0214-9. eCollection 2018.

A preliminary review of studies on adaptogens: comparison of their bioactivity in TCM with that of ginseng-like herbs used worldwide.

Liao LY1,2, He YF1,2, Li L1,2, Meng H1,2, Dong YM1,2, Yi F1,2, Xiao PG3.

Author information

1
1Key Laboratory of Cosmetics, China National Light Industry, Beijing Technology and Business University, No. 11/33, Fucheng Road, Haidian District, Beijing, 100048 People's Republic of China.
2
2Beijing Key Laboratory of Plant Resources Research and Development, Beijing Technology and Business University, No. 11/33, Fucheng Road, Haidian District, Beijing, 100048 People's Republic of China.
3
3Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 151 Malianwa North Road, Haidian District, Beijing, 100193 People's Republic of China.

Abstract

Modern studies have shown that adaptogens can non-specifically enhance the resistance of human body under a wide range of external stress conditions with a multi-targeted and multi-channel network-like manner, especially by affect the immune-neuro-endocrine system and the hypothalamic-pituitary-adrenal axis. This review article draws the attention to the relationships of adaptogens, tonics from traditional Chinese medicine (TCM) and ginseng-like herbs worldwide, which all have similar plant sources and clinical applications. To clarify the sources and pharmacological mechanisms of these plant-originated adaptogens, which will provide useful information for the utilization of adaptogens to improve the human health. Meanwhile, the TCMs and the world-wide ginseng-like herbs from each region's ethnopharmacology will be beneficial modernization and globalization.

KEYWORDS:

Adaptogen; Ginseng-like herbs worldwide; HPA axis; Immune-neuro-endocrine system; Tonics

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