Format

Send to

Choose Destination
Future Oncol. 2019 Feb;15(6):601-610. doi: 10.2217/fon-2018-0621. Epub 2018 Nov 27.

An observational study on the clinical features of esophageal cancer followed by multiple primary cancers.

Author information

1
Department of Cardiovascular Surgery, Renmin hospital of Wuhan University, 238 Jiefang Road, Wuhan City of Hubei Provice, PR China.
2
Department of Breast & Thyroid Surgery, Renmin hospital of Wuhan University, 238 Jiefang Road, Wuhan City of Hubei Provice, PR China.

Abstract

AIM:

To investigate the nature of multiple primary cancers initiated by esophageal cancer-multiple primary cancers (EC-MPC).

PATIENTS & METHODS:

SEER data about patients'/tumor characteristics, and survival were analyzed and compared.

RESULTS & CONCLUSION:

1727 of 29,733 registered EC patients have EC-MPC. Individuals diagnosed at 60-79 years old, earlier stage and/or moderately differentiated EC were more likely to get EC-MPC. Fewer patients in the EC-MPC group suffered from metastases. Patients in the EC-MPC group showed a longer survival rate and lower EC-specific deaths. Other factors like age, sex, race, tumor differentiation and Tumor, Node, Metastasis stage also affected survival. Radiation can improve survival. EC-MPC patients have some distinct features compared with solitary EC.

KEYWORDS:

esophageal cancer; multiple primary cancers; prognosis; therapy

PMID:
30477336
DOI:
10.2217/fon-2018-0621

Supplemental Content

Full text links

Icon for Atypon
Loading ...
Support Center