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Biosci Trends. 2018;12(5):515-516. doi: 10.5582/bst.2018.01254.

The importance of non-tuberculous mycobacteria identification in Chinese patients infected with HIV.

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Department of Infectious Disease, Shanghai Public Health Clinical Center, Fudan University.
Department of Infectious Disease, Huashan Hospital Affiliated to Fudan University.


The increased co-incidence of tuberculosis (TB) and AIDS is compounded by the emergence of opportunistic infections with non-tuberculous mycobacteria (NTM) in patients with HIV/AIDS, and the treatment for these infections differs from that for TB. The high frequency of NTM strains found in patients infected with HIV raises concerns about accurate species identification before deciding proper treatment. A total of 101 isolates from 2014, 137 from 2015, and 162 from 2016 were subjected to 16S rDNA sequencing to identify the species. Forty-one (41/101, 40.6%) were identified as NTM in 2014, 64 (64/137, 46.7%) were identified as NTM in 2015, and 72 (72/162, 44.4%) were identified as NTM in 2016 in Chinese patients infected with HIV. The species of Mycobacteria isolates needs to be rapidly and accurately identified to determine appropriate antibiotic therapy, and this is especially true for patients infected with HIV.


HIV; Non-tuberculous mycobacteria; identification; tuberculosis (TB)

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