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Pak J Pharm Sci. 2018 Nov 26. [Epub ahead of print]

Antibacterial, antifungal and enzyme inhibitory effects of selected plants from Turkey.

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Faculty of Pharmacy, Department of Pharmacognosy, Gazi University, Ankara, Turkey.
Faculty of Pharmacy, Department of Pharmaceutical Microbiology, Gazi University, Ankara, Turkey.
Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Faculty of Vocational Education, Department of Biology, Hacettepe University, Ankara, Turkey.


In this study, antibacterial, antifungal, antihyaluronidase, anticollagenase and antielastase activity of Hypericum bithynicum, Malva neglecta, Morus alba, Rubus discolor, Sambucus ebulus and Smilax excelsa were investigated. Methanol extracts of M. neglecta and R. discolor and all extracts of H. bithynicum were more active against Staphylococcus epidermidis. Similarly, water extracts of M. alba and S. ebulus were more active against Streptococcus pneumonia. Additionally, S. ebulus and S. excelsa had prominent antifungal activity on Candida albicans. Besides, methanol extract of M. neglecta and n-hexane extract of H. bithynicum were determined to have significant anti-hyaluronidase activity. Only R. discolor showed significant anti-elastase effect.


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