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Adv Exp Med Biol. 2018;1064:93-107. doi: 10.1007/978-981-13-0445-3_6.

Influence of Biomimetic Materials on Cell Migration.

Author information

1
Cellbiocontrol Laboratory, Department of Medical Engineering, Yonsei University College of Medicine, Seoul, South Korea.
2
Brain Korea 21 Plus Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea.
3
Cellbiocontrol Laboratory, Department of Medical Engineering, Yonsei University College of Medicine, Seoul, South Korea. parkjc@yuhs.ac.
4
Brain Korea 21 Plus Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea. parkjc@yuhs.ac.

Abstract

In recent tissue engineering applications, the advance of biomaterials has focused on the devising of biomimetic materials that are directing new tissue formation and capable of causing specific cellular responses. These advances can be controlled by modifying the devising parameters of the materials. The biomimetic materials potentially mimic many roles of ECM in tissues. For the homogeneous distribution and biocompatibility of scaffolds by cell migration with biomimetic materials, cell migration is studied because it has a important role in physiological phenomenon and in pathologies; cancer metastasis, immune response or embryonic development. This review discusses the migration of cells with biomimetic materials for tissue engineering. It is also summarized that the recent advances of cell migration with biomimetic materials in 2-D and 3-D for tissue engineering.

KEYWORDS:

Biomimetic material; Cell migration; Extracellular matrix; Scaffold; Tissue engineering

PMID:
30471028
DOI:
10.1007/978-981-13-0445-3_6
[Indexed for MEDLINE]

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