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Catheter Cardiovasc Interv. 2019 Mar 1;93(4):631-634. doi: 10.1002/ccd.27982. Epub 2018 Nov 23.

Case reports of coronary fibromuscular dysplasia and spontaneous coronary artery dissections.

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Division of Cardiology, Vancouver General Hospital, University of British Columbia, Canada.


Spontaneous coronary artery dissection (SCAD) is an important cause of acute coronary syndrome especially in women. The most common underlying predisposing cause of SCAD is fibromuscular dysplasia (FMD), a non-inflammatory arteriopathy that results in weakening of the affected arteries, and can cause dissection or aneurysm. Coronary FMD (CFMD) was described as rare, and was shown to cause SCAD in histopathological case reports. Unfortunately, CFMD is challenging to diagnose on coronary angiography, as the findings can be similar to other causes of coronary artery disease. Therefore, we illustrate two case examples of CFMD on coronary angiography, and highlight findings on optical coherence tomography to aid diagnosis.


fibromuscular dysplasia (FMD); myocardial infarction; spontaneous coronary artery dissection (SCAD)


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