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J Pediatr. 2018 Nov 19. pii: S0022-3476(18)31545-2. doi: 10.1016/j.jpeds.2018.10.038. [Epub ahead of print]

Caution Is Required When Using Non-Food and Drug Administration-Cleared Assays to Diagnose Sexually Transmitted Infections in Children.

Author information

1
Mayerson Center for Safe and Healthy Children, Cincinnati Children's Hospital, Cincinnati, OH. Electronic address: abrownell@spurwink.org.
2
Mayerson Center for Safe and Healthy Children, Cincinnati Children's Hospital, Cincinnati, OH.
3
Department of Pediatrics, Division of Infectious Diseases, State University of New York, Downstate Medical Center, Brooklyn, NY.

Abstract

Nucleic acid amplification testing is the gold-standard for Chlamydia trachomatis and Neisseria gonorrhoeae testing in adults. We present 3 pediatric cases in which testing resulted in probable false-positive results. Clinicians should avoid tests without clearance from a regulatory agency and should maintain consistent communication with laboratories.

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