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Hua Xi Kou Qiang Yi Xue Za Zhi. 2018 Oct 1;36(5):559-563. doi: 10.7518/hxkq.2018.05.017.

[The role of bone morphogenetic protein signaling pathway in tooth root development].

[Article in Chinese; Abstract available in Chinese from the publisher]

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Dept. of Oral Pathology, School and Hospital of Stomatology, Jilin University, Key Laboratory of Tooth Development and Bone Remodeling of Jilin Province, Changchun 130021, China.


in English, Chinese

The bone morphogenetic protein (BMP) family is an important factor in the regulation of cell ular life activities and in the development of almost all tissues. BMP-mediated signaling plays an important role in tooth root development, which is a part of tooth development. Epithelial and mesenchymal interactions are involved in tooth root development, but the BMP signaling pathway has a different effect on tooth root development in epithelial and mesenchymal. This review summarizes the advances of BMP signaling in tooth root development.


bone morphogenetic protein; epithelial root sheath; odontogenesis

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