[Study of tumor-specific expression of some evolutionary new genes]

L L Krukovskaya; D E Polev; T V Kurbatova; Y X Karnaukhova; A P Kozlov

[Study of tumor-specific expression of some evolutionary new genes]

Vopr Onkol. 2016;62(3):495-500.

[Article in Russian]

Authors

L L Krukovskaya, D E Polev, T V Kurbatova, Y X Karnaukhova, A P Kozlov

PMID: 30463107

Abstract

In this paper we have showed that evolutionary new genes DCD1(Dermicidin), LINC00309 (Long intergenic non-protein coding RNA 309) and CLLU1(Chronic lymphocytic leukemia up-regulated 1) have tumor-specific expression profile. Along with our previously published results this confirms the existence of the phenomenon of TSEEN (Tumor-Specifically Expressed, Evolutionarily Novel).

MeSH terms

Biomarkers, Tumor / genetics
Evolution, Molecular
Female
Gene Expression Regulation, Neoplastic
Humans
Male
Neoplasm Proteins / genetics*
Neoplasms / classification
Neoplasms / genetics*
Neoplasms / pathology
Peptides / genetics*
RNA, Long Noncoding / genetics*

Substances

Biomarkers, Tumor
CLLU1 lncRNA, human
Neoplasm Proteins
Peptides
RNA, Long Noncoding
dermcidin